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Third Harmonic Bio is nearing an IND submission to put a new oral KIT inhibitor into the clinic
CEO Natalie Holles describes how learnings from a setback from the company's first asset have resulted in a new program.
Mar 4, 2024


BlossomHill Therapeutics raises a $100M series B to work on precision medicine small molecules
Scientific founder, president & CEO J. Jean Cui describes her scientific approach of working to solve resistance mutations.
Mar 1, 2024


Pravin Dugel on taking the job of executive chairman at Ocular Therapeutix
He describes what made him excited about the company, and why he views diabetic retinopathy as potentially a bigger opportunity than wet AMD
Feb 26, 2024


Legend Biotech's CEO Ying Huang on moving CARVYKTI into earlier lines of treatment in the E.U. and U.S.
Ying Huang talks about Friday's CHMP positive opinion and the upcoming FDA advisory committee meeting, and highlight's Legend's pipeline.
Feb 26, 2024


Talking siRNAs with the CEO of Silence Therapeutics
Craig Tooman describes Silence's two lead programs targeting Lp(a) and polycythemia vera, as well as the company's broader platform.
Feb 26, 2024


Lyell Immunopharma's CEO on the future of TIL and CAR-T therapies for solid tumor targets
On the heels of a historic recent approval for the class, Lynn Seely describes the science behind TIL therapies.
Feb 26, 2024


Nobel laureate Carolyn Bertozzi on the launch of Firefly Bio and the science of degrader antibody conjugates
Carolyn Bertozzi introduces Firefly and explains the idea behind combining the science of antibody-drug conjugates with protein degraders
Feb 16, 2024


A deep dive into the science of immuno-neurology with the CEO of Alector
Arnon Rosenthal walks us through the idea of the immune system playing a central role in neuro-degeneration
Feb 15, 2024


ALX Oncology's CEO on CD47 after Gilead's magrolimab news last week, and why he believes his asset is fundamentally different
Jason Lettmann describes how he believes having an inactive Fc domain makes all the difference in the CD47 space.
Feb 14, 2024


Taking a deep dive into the IgA nephropathy (IgAN) space with the CEO of Vera Therapeutics
Marshall Fordyce describes the rationale of targeting both BAFF and APRIL as a B-cell modulator for IgAN.
Feb 13, 2024


A deep dive into the science of prime editing with the CEO of Prime Medicine
Prime Medicine CEO Keith Gottesdiener describes the advantages he sees in prime editing.
Feb 9, 2024


Lexeo Therapeutics' CEO on using gene therapy for cardiovascular and Alzheimer's disease
Noland Townsend describes the science behind Lexeo's lead programs.
Feb 2, 2024


Alto Neuroscience's CEO on today's $128.6 million NYSE IPO
Amit Etkin describes Alto's approach to tyring to bring precision medicine to psychiatry.
Feb 2, 2024


The growth of RNAi as a platform with the CEO of Arrowhead Pharmaceuticals
Arrowhead CEO Chris Anzalone discusses the present and future of RNAi, and speaks on the company’s cardiometabolic and pulmonary programs.
Feb 1, 2024


ImmPACT Bio's CEO on bispecifc CAR-T cells for cancer and autoimmune disease
Sumant Ramachandra describes why ImmPACT's programs target more than one antigen and the case for CD19/CD20 in oncology and autoimmune.
Feb 1, 2024


Terray Therapeutics' CEO on designing computational and experimental platforms to supercharge small molecule discovery
Jacob Berlin walks on the process that has allowed Terray to do well over 2 billion target / ligand binding measurements over 18 months.
Jan 31, 2024


The Science Behind the News: Ascidian Therapeutics' IND is cleared for an RNA exon editing program against Stargardt disease
Ascidian Interim President & CEO Mike Ehlers explains the scientific concept of RNA exon editing
Jan 29, 2024


Ovid's Jeremy Levin on advances in CNS, soticlestat, ROCK2, Washington and more
Jeremy Levin walks us through the science of Ovid's CNS-focused pipeline, gives his take on the health of the biotech.
Jan 22, 2024


Roivant's Matt Gline on the success of Telavant, Immunovant's FcRn program, and his expectations for the company's cash usage
Matt Gline reflects on learnings from the Telavant success, and why he thinks Immunovant's FcRn might be best in class.
Jan 22, 2024


Axsome's CEO on the launches of Auvelity and Sunosi, and the year ahead
Herriot Tabuteau on his company's recent launches, submissions migraine and fibromyalgia, key data in narcolepsy and Alzheimer's, and more.
Jan 22, 2024








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