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Taking a deep dive into last week's T-cell engager data with the CEO of Janux Therapeutics
David Campbell explains how Janux has used masking technology to improve the profile T-cell engagers in solid tumors.
Mar 6, 2024


Cellarity's CEO on harnessing technology to better understand disease from a whole cell approach
Fabrice Chouraqui describes Cellarity's platform and how it is being put to use for indications such as sickle cell disease and MASH.
Mar 5, 2024


Frontier Medicines is leveraging a chemoproteomics platform to try to build a better KRAS G12C
Chris Varma describes why hitting KRAS G12C in both its on and off state could be an improvement over existing medicines.
Mar 5, 2024


New Amsterdam Pharma is trying to revive the CETP class for cardiovascular disease
CEO Michael Davidson describes how Obicetrapib, which was reacquired from Amgen, is designed to produce more LDL lowering than others.
Mar 5, 2024


Third Harmonic Bio is nearing an IND submission to put a new oral KIT inhibitor into the clinic
CEO Natalie Holles describes how learnings from a setback from the company's first asset have resulted in a new program.
Mar 4, 2024


Nuvalent's CEO on overcoming kinase resistance and selectivity for its precision oncology medicines
Jim Porter describes the chemistry that has led to early stage success against ALK and ROS1.
Mar 4, 2024


Black Diamond Therapeutics' CEO on the company's 'MasterKey' approach to precision oncology
Mark Valleca describes Black Diamond's 'MasterKey' approach to precision oncology that's aimed at solving many mutations at once.
Mar 4, 2024


BlossomHill Therapeutics raises a $100M series B to work on precision medicine small molecules
Scientific founder, president & CEO J. Jean Cui describes her scientific approach of working to solve resistance mutations.
Mar 1, 2024


Using NK cell therapies for autoimmune disease and cancer with Artiva's CEO
Fred Aslan describes how Artiva is harnessing the ability of NK cells to act as a modulator of antibody dependent cellular cytotoxicity.
Mar 1, 2024


Mathai Mammen on being back to company building at Fog Pharma
He describes how Fog is leveraging the way α-helices mediate interactions with other proteins to solve the undruggable problem.
Feb 28, 2024


5AM Ventures' Andy Schwab shares his take on biotech cycles and key themes of today
Andy Schwab describes founding 5AM in 2002 and discusses portfolio companies Radionetics, Latigo, TMRW, and Skye Bioscience.
Feb 28, 2024


Biocom California's CEO on this week's Global Partnering and Investor Conference in La Jolla
Joseph Panetta introduces the conference and we discuss the state of biotech in California's numerous biotech hubs.
Feb 28, 2024


Pfizer Ignite and StudioLabs by Breakthrough Properties announce Partnership
Pfizer Ignite and StudioLabs by Breakthrough Properties are partnering to help biotech entrepreneurs get to work and succeed.
Feb 26, 2024


Yaron Werber previews the 44th Annual TD Cowen Health Care Conference
He discusses some of the key theme of the conference including obesity, IgG, ATTR cardiomyopathy, and more.
Feb 26, 2024


Pravin Dugel on taking the job of executive chairman at Ocular Therapeutix
He describes what made him excited about the company, and why he views diabetic retinopathy as potentially a bigger opportunity than wet AMD
Feb 26, 2024


Legend Biotech's CEO Ying Huang on moving CARVYKTI into earlier lines of treatment in the E.U. and U.S.
Ying Huang talks about Friday's CHMP positive opinion and the upcoming FDA advisory committee meeting, and highlight's Legend's pipeline.
Feb 26, 2024


Talking siRNAs with the CEO of Silence Therapeutics
Craig Tooman describes Silence's two lead programs targeting Lp(a) and polycythemia vera, as well as the company's broader platform.
Feb 26, 2024


Lyell Immunopharma's CEO on the future of TIL and CAR-T therapies for solid tumor targets
On the heels of a historic recent approval for the class, Lynn Seely describes the science behind TIL therapies.
Feb 26, 2024


Searching for novel targets in IO with the co-founder and CEO of Cartography Biosciences
Kevin Parker describes how Cartography has been building an antigen map over previous years.
Feb 23, 2024


Stifel's Paul Matteis covers earnings season and recent clinical data in biotech on Analyst Thursdays
Paul Matteis gives his take on biotech's start to the year and comments on Alnylam, Biogen, Vertex, KalVista, Denali, Acadia, and more.
Feb 22, 2024