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The CEO of Jasper Therapeutics on c-KIT inhibition
Ronald Martell describes Jasper's subcu programs for urticaria.
Apr 22, 2024


Visiting Adaptimmune on its investor day and ahead of this year's FDA decision for the TCR cell therapy afami-cel in synovial sarcoma
CEO Adrian Rawcliffe describes how Adaptimmune is preparing to launch what could be the first approved TCR based cell therapy in the U.S.
Apr 18, 2024


Ultragenyx's Emil Kakkis on this week's Angelman syndrome data, rare disease treatment modalities, and more
Emil Kakkis summarizes Ultragenyx's Angelman syndrome update at AAN and more.
Apr 16, 2024


The CEO of Madrigal on the launch of Rezdiffra for NASH liver disease
Bill Sibold describes how Madrigal has prepared for the launch and illustrates how the medicine is meant to impact disease progression.
Apr 10, 2024


AACR24: Having entered the clinic last night, Nested's CEO discusses the preclinical profile of a brain-penetrant, pan-RAF/MEK molecular glue
Darrin Miles describes how this molecular glue therapy has been designed to bind to MEK and all isoforms of MEK and RAF in combination.
Apr 9, 2024


AACR24: EpicentRx’s phase 2a using TGF-β trap to overcome checkpoint resistance
EpicentRx CEO Tony Reid and MD Andersen investigator Anthony Conley describe TGF-β data presented at AACR.
Apr 9, 2024


Daphne Zohar on becoming the CEO of Seaport Therapeutics and today's $100M series A
She describes working with Steven Paul again, the Glyph technology that is the backbone of Seaport's platform, and more.
Apr 9, 2024


Syncromune's AACR late-breaker of phase 1 data for the SYNC-T immunotherapy drug-device combo in mCRPC
CEO Eamonn Hobbs describes the responses Syncromune is seeing in an early phase 1 prostate cancer study.
Apr 8, 2024


Carisma Therapeutics' CEO on refocusing its pipeline this week and what the company has learned in the clinic
CEO Steven Kelly described the scientific basis of pipeline changes they have made this week and when we can expect to see data.
Apr 4, 2024


Sutro Biopharma's CEO on ADCs, non-cell protein synthesis, and more
Bill Newell describes this week’s deal with Ipsen, the folate receptor alpha space, and more.
Apr 4, 2024


San Diego's Alterome Therapeutics raised a $132M Series B today for its precision oncology platform
Co-Founder and CEO Eric Murphy describes what it was like raising the money in this environment.
Apr 3, 2024


Spun out of Paragon, Oruka Therapeutics raised $275M today as part of a reverse merger to tackle skin conditions in the I&I space
CEO Lawrence Klein describes advances in antibody engineering Oruka is leveraing to make improved IL-23 and IL-17 inhibitors.
Apr 3, 2024


Verve Therapeutics' CEO on today's gene editing clinical trial pause
Sek Kathiresan describes what Verve believes caused elevated liver enzymes and thrombocytopenia in a PCSK9 gene editing trial.
Apr 2, 2024


Kyverna's CEO on B-cell depletion and CD19 CAR-T for autoimmune conditions
Peter Maag describes how Kyverna has been focused on this area for five years.
Mar 27, 2024


Nkarta CEO Paul Hastings on NK based cell therapies for autoimmune conditions
Paul Hastings describes why Nkarta believes NK based therapies are uniquely fit for this area.
Mar 27, 2024


Checking in with Geron's CEO after imetelstat's recent ODAC meeting
John Scarlett shares his take on imetelstat's clinical utility, potential commercial dynamics, the IP situation, and more.
Mar 26, 2024


Mirador Therapeutics launched with a $400M+ fundraising round today for precision medicine in the I&I space
Founder Mark McKenna describes the unmet need that exists in the I&I space.
Mar 21, 2024


MeiraGTx's CEO on the gene therapy field and upcoming data her company will have over the coming quarters
Alexandria Forbes describes the investments MeiraGTx has made in manufacturing and how it is helped progress various programs.
Mar 19, 2024


Taking a deep dive into last week's T-cell engager data with the CEO of Janux Therapeutics
David Campbell explains how Janux has used masking technology to improve the profile T-cell engagers in solid tumors.
Mar 6, 2024


Frontier Medicines is leveraging a chemoproteomics platform to try to build a better KRAS G12C
Chris Varma describes why hitting KRAS G12C in both its on and off state could be an improvement over existing medicines.
Mar 5, 2024








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