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AI Proteins Founder & CEO Chris Bahl and Dana-Farber Cancer Institute Investigator Nick Polizzi discuss the current state of protein design and new innovations that are around the corner
Both experts in the field, one with an academic view and one from industry, they discuss what can be done today with protein design, new innovations coming in the next year or two, and how they think about improving selectivity and sensitivity. Plus, how AI is changing the field, what it takes to be differentiated, and implications of new startups sharing less knowledge than has been traditionally done. Chapters The current state of the art – 1:05 What is coming in the next y
5 hours ago


Quell Tx believes that restoring immune balance rather than entirely depleting cells is key for many autoimmune conditions - a phase 1/2 for its CAR-Treg initiated today in RA & Systemic Sclerosis
CEO Iain McGill describes the "Chill, not Kill" approach that Quell is taking with its Treg platform, which integrates a FOXP3 phenotype lock in addition to the CAR. Plus, an update on the company's liver transplant study, a program that he says will need a partner to move forward.
2 days ago


Welcoming Wassim Laroussi to the BiotechTV team
Wassim will be a Markets Correspondent contributing content that reports on biotech news, and includes explainers and commentary on it.
3 days ago


BioVenture VoiCes Episode 35: INITIATE Ventures' Jessica Owens
Jessica Owens discusses the many experiences she has had in her career, including working on the venture side at Kleiner Perkins and Versant Ventures and on the operating side at Genomic Health and Grail. She highlights the value of VCs being able to understand how operators like CEOs think, and describes the type of investing INITIATE focuses on. Chapters Intro and early life - 0:49 First jobs / Wall Street - 13:25 Kleiner Perkins - 17:04 Kauffman Fellow - 24:14 Versant Vent
Feb 23


Protagonist Therapeutics has two medicines in front of FDA right now - we discuss the expertise in peptide based drug development that has enabled them to get to this point
CEO Dinesh Patel and Chief Discovery Officer Ashok Bhandari walk us through the company's R&D expertise, and we discuss programs covering IL-23, IL-17, a hepcidin mimetic, and obesity medicines.
Feb 19


Cambridge, UK based Arecor uses formulation and development expertise to improve the profile of medicines - the company believes it has its own best in class insulin leveraging this
CEO Sarah Howell discusses three key aspects of the business: helping with reformulation, its own proprietary insulin products, and developing oral peptides like GLPs.
Feb 18


NewLimit is using epigenetic reprogramming to bring cells back to a younger and healthier state, thus tackling age related disease
Co-Founder & President Jacob Kimmel describes the science behind how this works, and the enormous amount of work that goes into choosing which transcription factors to target. The company is currently in IND enabling studies.
Feb 18


Gordian Biotechnology announced that it will be using its unique large-scale in vivo screening process to help Pfizer look for new targets against obesity
Co-Founder & CSO Martin Borch Jensen describes the deal and walks us through Gordian's process that enables it to do a multiplicity of in vivo screening in months that previously would have taken years.
Feb 18


Cambridge, UK based Microbiotica announced results from a phase 1b trial of its microbiome treatment MB310 in ulcerative colitis showing a 63% remission rate
CEO Tim Sharpington and CMO Robert Tansley walk us through the treatment, which contains a defined consortium of eight live gut commensal bacterial strains, and the data.
Feb 18


Ocular Therapeutix Chair & CEO Pravin Dugel discusses the result of today's SOL-1 phase 3 superiority trial of AXPAXLI vs EYLEA in wet AMD
The study showed that AXPAXLI has superior maintenance of visual acuity at Week 36 vs EYLEA. Dr. Dugel discusses what he believes the significance of this is, and delves into durability data going out to 52 weeks.
Feb 17


Oxford based Infinitopes raised an additional $15.4M in a second closing of its seed round to bring the total raised to $35.1M. It will have clinical data on its cancer vaccine by the end of the year
Co-Founder & CEO Jonathan Kwok describes the company's platform, which helps it identify highly expressed and immunogenic tumor antigens, and how the lead program for oesophageal cancer will have data by the end of 2026.
Feb 17


From Oxford: Carlo Rinaldi's team has received two grants from Oxford-Harrington Rare Disease Centre to develop treatments for Spinal-bulbar muscular atrophy (SBMA) and Friedreich's ataxia
He describes his work in these diseases and how Oxford-Harrington has provided funding and advice that has been valuable beyond the feedback he typically receives in an academic setting.
Feb 17


From Oxford: Professor Matthew Wood describes the Oxford-Harrington Rare Disease Centre, a transatlantic effort to accelerate drug development for rare diseases
He highlights the centre's Scholars program, which researchers anywhere can apply for and funds ten new drug development programs each year. Plus the centre's accelerator program and plans for a rare disease investment fund. He also discusses how regulatory changes at places like MHRA can help the rare disease community.
Feb 17


Biotech CEOs discuss the state of the industry, what is needed to compete globally, the importance of having a patient-centric approach, and more
MassBio President & CEO Kendalle Burlin O'Connell moderates a discussion with Aurora Therapeutics CEO Ed Kaye and DaCapo Brainscience CEO Leslie Williams about being biotech leaders during this volatile time for the industry. They stress that a key to success is that everyone in the industry work together towards shared goals. Chapters Introductions - 1:19 Aurora Therapeutics - 5:34 DaCapo Brainscience - 9:37 Being patient centric - 11:00 The state of the industry - 19:04 Mas
Feb 12


Analyst Thursdays: Mizuho Senior Biotech Analyst Graig Suvannavejh shares his take on three key biotech trials that are scheduled to read out soon, and one that recently happened
He discusses upcoming readouts for IDEAYA Biosciences, Ocular Therapeutix (how it might affect EyePoint), and Palvella Therapeutics. Plus, his take on the recent Corvus atopic dermatitis data. Chapters IDEAYA Biosciences - 0:46 EyePoint / Ocular - 3:45 Palvella - 7:43 Corvus - 12:30
Feb 12


Upstream Bio's CEO Rand Sutherland discusses today's severe asthma data for verekitug, a TSLP receptor antagonist
He describes top-line data the company saw across three different doses, next steps, and also shares an update on additional indications of chronic rhinosinusitis with nasal polyps and COPD it is being developed for.
Feb 11


The Massachusetts Life Sciences Center hosted Convening of the Cores at The Engine in Cambridge today to showcase publicly-available scientific equipment and facilities biotech companies can access
MLSC's President & CEO Kirk Taylor, MD describes the organization's mission, how biotech startups and others can search for and utilize equipment and facilities that might otherwise be out of reach, and his take on the current state of the ecosystem.
Feb 10


SLAS 2026: Atinary showed BiotechTV the "Self Driving Lab" it has created in the Seaport that integrates machine learning into the experiment design and optimization process to accelerate science
Co-Founder & CEO Hermann Tribukait explains how integrating AI, robotics, and human expertise can make drug discovery happen at a new speed.
Feb 10


BioVenture VoiCes Episode 34: General Atlantic's Brett Zbar
Brett Zbar describes his early career, including working at Aisling Capital and Foresight Capital, and now managing the healthcare strategy at General Atlantic. He describes how he sees the difference between private equity and venture capital, and discusses which themes in biotech and healthcare appeal to him today. Chapters Intro and early life – 0:54 Medical school, residency, and industry experience – 5:58 McKinsey – 11:05 Aisling – 14:35 Foresight Capital – 19:11 General
Feb 9


AI News: GATC Health has created an AI platform to predict clinical trial outcomes - it is already being used for things from insuring clinical trials to helping with pipeline optimization
GATC's Ty Lam describes how it works and the various use cases the company has been pursuing, including doing their own discovery work.
Feb 4






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