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Pliant's CEO on targeting integrins to treat fibrotic diseases like IPF and liver disease
Bernard Coulie gives a deep dive into Pliant's IPF program, including news released this morning relating to patient PET scans.
May 14, 2024


Xenon's CEO on Kv7 potassium channel modulation in the CNS space and his thoughts on NaV1.7/1.8 for pain
Ian Mortimer gives the rationale for Kv7 in epilepsy and major depressive disorder, and explains why Xenon has chosen the NaV1.7 sodium...
May 14, 2024


The CEO of Corbus on nectin-4 ADCs, integrin biology, and an alternative to GLPs for weight loss
Yuval Cohen describes why he believe his company's nectin-4 ADC has a next generation design, he covers the idea of integrin inhibition...
May 14, 2024


RBC's Brian Abrahams kicks off the 2024 RBC Capital Markets Global Healthcare Conference
Brian Abrahams previews the conference, shares his take on biotech, and offers some themes to watch throughout the remainder of the year.
May 14, 2024


Visiting the future site of Trinity by Breakthrough in Oxford, UK
Thomas Renn, Head of Europe for Breakthrough Properties, introduces us to this state-of-the-art facility that will encompass 214,000...
May 13, 2024


Tome Biosciences' CEO on the company's 'Programmable Genomic Integration' platform and NHP data presented at #ASGCT2024
Rahul Kakkar describes how PGI is being leveraged for both gene and cell therapy applications.
May 10, 2024


In humanized mouse models, Tessera is demonstrating LNP delivery of gene writers to, and rewriting of, hematopoietic stem cells to an extent that could be curative in sickle cell disease
CEO Mike Severino describes the sickle cell data Tessera is presenting at #ASGCT2024, and highlights the company's gene writing platform...
May 10, 2024


Ring Therapeutics believes that the next great viral vector is a ubiquitous, but little known, family of viruses already found in the body
Ring CEO Tuyen Ong introduces us to anelloviruses and describes the qualities that could make them compelling delivery vehicles. Animal...
May 9, 2024


ProQR's CEO at #ASGCT2024 on NHP proof-of-concept data for the company's Axiomer RNA-editing platform
Daniel de Boer describes how Axiomer harnesses the body's natural ADAR editing process to turn an A into an I, he covers NHP data for...
May 9, 2024


Ascidian presented NHP and human retinal explant data at #ASGCT2024 suggesting proof of concept for its RNA exon editing approach
Head of research Robert Bell described the preclinical data in a Stargardt disease model that has led to an IND acceptance for this...
May 9, 2024


Attovia Therapeutics raised a $105M series B today to take on the I&I space, including designing multi-target bispecifics
Founder & CEO Tao Fu walks us through the company's ATTOBODY platform and discusses programs targeting IL31 and IL31 x IL13.
May 9, 2024


Genetic medicines expert Emily Walsh Martin shares learnings from Day 2 of #ASGCT2024
Emily Walsh Martin covers regulatory comments from FDA's Peter Marks, scientific updates on prime and base editing, and more.
May 8, 2024


SalioGen’s CEO on the company’s ‘Gene Coding’ approach to genetic medicine and an oral presentation today at #ASGCT2024 for its Stargardt disease program
Jason Cole describes how Gene Coding can deliver large sequences to the genome without viral vectors or RNA guides, and describes how...
May 7, 2024


Previewing the 2024 ASGCT Annual Meeting in Baltimore with gene editing expert TJ Cradick
TJ Cradick gives us a preview of which abstracts and technologies to watch this year, including the latest in gene editing methods and...
May 7, 2024


A computational biologist and assistant professor at Philadelphia’s Wistar Institute on positives and potential negatives of AI’s emergence to the forefront of life sciences
An early adopter and researcher of AI, Noam Auslander shares her opinion of the benefits of AI but also guardrails that should be...
May 6, 2024


Founder Mark Kotter describes the science that has enabled bit.bio to design and manufacture virtually any cell type and characteristic from iPSCs
He explains how machine learning has allowed bit.bio to model which transcription factor combinations are needed to create a desired cell...
May 6, 2024


Ochre Bio CEO Jack O'Meara discusses his company's focus on liver diseases and its recent Boehringer Ingelheim partnership
Jack O'Meara describes Ochre's unique preclinical testing strategy as it develops siRNA drugs for liver diseases, and he touches on a...
May 6, 2024


How Cambridge Innovation Capital has become a preeminent investment firm in Cambridge life sciences, and also a significant attractor of outside capital to Cambridge
CIC Partner Michael Anstey describes the firm's history and investment approach, lists some current investments, and offers advice for...
May 6, 2024


A pioneer in fragment based drug discovery, Harren Jhoti describes how Astex Pharma has contributed to three now approved medicines since its founding in Cambridge in 1999
Dr. Jhoti discusses the history of Astex, shows us a state-of-the-art cryo-EM microscope they have on site, and highlights the three...
May 6, 2024


Innovate Cambridge's new executive director shares an overview of the key points and institutions to know within Cambridge life sciences
Kathryn Chapman has held many roles in town and is an expert on everything Cambridge's life sciences ecosystem has to offer.
May 5, 2024